MENU

 
Thyroid Disorder and Bipolar Disease

Sub optimal thyroid levels - even within normal range - may affect clinical outcomes in bipolar disorder

As the instruments of laboratory science become more precise, so too does our understanding of how even slight biochemical imbalances in the body may potentially affect human health.

A new study funded by the National Institute of Mental Health reports that as many as two out of every three patients with bipolar depression may have sub optimal thyroid hormone levels. These slight
imbalances, though still within the "normal range," appear to make these patients much more resistant to standard drug treatments with anti-depressants.

Researchers measured thyroid hormone levels in 65 patients diagnosed in the depressive phase of bipolar disorder. For the next 50 months, they tracked their recovery after treatment with mood-stabilizing drug therapies, including lithium carbonate and various antidepressant medications.

While it's already well known that both overt and sub clinical thyroid dysfunction are strongly linked with depression, the effect of more subtle thyroid imbalances has not yet been thoroughly studied.

The study found that patients with low normal levels of free thyroxin (T4) index or high normal levels of thyroid-stimulating hormone (TSH) levels were much less responsive to various drug treatments for depression. On average, these patients took nearly one year to respond to drug therapy - at least four months longer than patients who had an optimal thyroid profile.

Thyroid hormone imbalances in these patients could develop as the central nervous system becomes unable to self-regulate itself properly under the stress of chronic depression. The imbalances could also be a first early warning signal that thyroid failure is more likely to develop in these patients in the future.

"…it appears likely that patients with mood disorders are particularly vulnerable to even minor variations in thyroid hormone levels," researchers concluded. The imbalances that produced an effect on treatment outcomes were even milder than those falling under the sub clinical definition of hypothyroidism. For this reason, a sub optimal thyroid profile - still within the "normal" range - may be an important modifiable risk factor in bipolar depression.

"These results add to the growing literature in support of the idea that thyroid measures in the low normal range may result in a less than optimal outcome in mood disorders," the study asserted.

NOTE: The Comprehensive Thyroid Assessment is a thorough functional evaluation of central and peripheral thyroid metabolism and thyroid auto immunity, specially designed to reveal subtle, pre clinical imbalances. Because the thyroid is the main regulator of human metabolism, even slight imbalances can affect a wide range of physiological and psychological conditions, including mood disorders, obesity, chronic fatigue, digestive problems, cognitive and sexual dysfunction, and cardiovascular disease.

In addition to analyzing central thyroid regulation (TSH and free T4) and thyroid auto immunity (anti-TG and anti-TPO), this in-depth assessment evaluates peripheral thyroid function using free T3, rT3, free T3/rT3 ratio, and free T4/free T3 ratio. Each test report displays markers within their functional metabolic pathways for increased clinical relevance and insight, with professional commentary based on individual results. Find out more about the test click on the link above "The Comprehensive Thyroid Assessment.

Source: Cole DP, Thase ME, Mallinger AG, Soares JC, Luther JF, Kupfer DJ, Frank E. Slower treatment response in bipolar depression predicted by lower pretreatment thyroid function. Am J Psychiatry 2002;159:116-121.

Call to set up a nutritional consultation so that tests can be performed and a comprehensive strategy of lifestyle, dietary modification and nutrient supplementation can be implemented to aid you in reversing this disorder.

Teresa Rispoli has her Ph.D. in Nutrition, is a licensed Acupuncturist and clinical researcher. She has been in practice for well over 25 years. It is through her clinical practice that she has gained insights into chronic health conditions. If you are suffering from unexplained symptoms that come and go you owe it to yourself to find out why. Find out today call for a Nutritional Consultation with Dr. Rispoli.

Your happiness is a reflection of your health call today For an appointment, contact her office at (800) 956-7083 or (818) 707-3125.

We also offer Functional Laboratory tests that can be done through the mail in the privacy of your home to help determine why you are having these symptoms. For more information on these click on lab tests.

****************


Call 818-707-3126 to set up a Nutritional Consultation so that Dr. Rispoli can get to the root of your health concern, design a therapeutic diet and or comprehensive strategy of lifestyle changes, and nutritional support to aid you in the direction of wellness.

We also offer Functional Laboratory tests that can be done through the mail in the privacy of your home, to get to the root of your health concerns. Just choose lab tests and click on test of interest.

Click on Related Articles or Products to the left for more information.

Teresa Rispoli has her Ph.D. in Nutrition, is a licensed Acupuncturist, Master Herbalist, Certified Functional Nutritionist, has a Doctorate in Naturopathy and is a clinical researcher, and Licensed Esthetician. She has been in practice for well over 27 years. It is through her clinical practice that she has gained insights into chronic health conditions. If you are suffering from unexplained symptoms that come and go you owe it to yourself to find out why. Find out today call for a Nutritional Consultation with Dr. Rispoli.

If you are suffering from unexplained symptoms yourself to find out why. Find out today call for a Nutritional Consultation with Dr. Rispoli.

Remember that the body can heal itself if given the proper nutrients with the right environment and lifestyle.

Dr. Rispoli will help guide you to make the right choices for your individual needs. Teresa Rispoli will work with you to teach you which program is right for you so you can make informed decisions regarding your health.

She is the founder and Director for Complete Health. She will find the root of your health issues, from a Functional Health perspective, and personalize a health building program to help you experience vibrant health.

Schedule your Wellness Consultation TODAY with Dr. Rispoli

Call 818-707-3126.

Yours For Inner Health and Outer Beauty,
Teresa Rispoli, DCN, CFN, LAC.

If you'd like to receive your own Complete Health E Newsletter, please sign up on our website: www.completehealthinstitute.com

We have a strict anti-spam policy. We know how important your privacy is to you. That's why we do not share your email address with anyone. Click here to read our Privacy Policy

To Contact Us:
Complete Health
28247 Agoura Rd
Agoura Hills, CA 91301
818-707-3126
support@completehealthinstitute.com

To unsubscribe from future mailings, reply with "unsubscribe".

Let us know if you like this article.