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Rheumatoid Arthritis and Oxidative Stress

Free radicals are highly reactive molecules in the body that can cause damage by destroying enzymes, protein molecules and entire cells. The oxidative damage caused by free radicals is a pivotal mechanism implicated in the progression of rheumatoid arthritis.

Because oxygen free radicals mediate tissue and joint damage in patients with rheumatoid arthritis, these patients often exhibit much higher levels of oxidation.1-3 In fact, researchers have found that low antioxidant status can actually serve as a risk factor for developing rheumatoid arthritis.4

Another study linking the inflammation process in rheumatoid arthritis with oxidative markers concluded that laboratory analysis of free radical action, such as the Oxidative Stress Analysis, could be used to monitor progress in the treatment of this and other rheumatic diseases.5

Call to set up a nutritional consultation so that tests can be performed and a comprehensive strategy of lifestyle, dietary modification and nutrient supplementation can be implemented to aid you in reversing this disorder.

For an appointment, contact our office at: 800-956-7083 or 818 707-3126.

Dr. Rispoli, Ph.D., L.Ac. has had a clinical practice for over 20 years. Her programs work because she is so thorough in testing and providing a nutritional approach. Remember that the body can heal itself if given the proper nutrients.


All lab tests can be done through the mail in the privacy of your own home, except blood tests, we send you to a lab to have your blood drawn for these. After you pay for the test we mail you the kit, the results take two weeks, the test results will be mailed to us and we will call you to go over the results, its that easy! All tests include the consultation for the report of findings.

References:
1 Kaur H, Edmonds SE, Blake DR, Halliwell B. Hydroxyl radical generation by rheumatoid blood and knee joint synovial fluid. Ann Rheum Dis 1996;55(12):915-920.
2 Comstock GW, Burke AE, Hoffman SC, Helzlsouer KJ, Bendich A, Masi AT, Norkus EP, Malamet RL, Gershwin ME. Serum concentrations of alpha tocopherol, beta carotene, and retinol preceding the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 1997;56(5):323 325.
3 Lunec J, Halloran SP, White AG, Dormandy TL. Free-radical oxidation (peroxidation) products in serum and synovial fluid in rheumatoid arthritis. J Rheumatol 1981;8(2):233-245.
4 Heliovaara M, Knekt P, Aho K, Aaran RK, Alfthan G, Aromaa A. Serum antioxidants and risk of rheumatoid arthritis. Ann Rheum Dis 1994;53(1):51-53.
5 Kucera M, RacedJ, Holecek V. Free oxygen radicals and rheumatic diseases. Vnitr Lek 1996;42(5):320-323.


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