The Metabolic Analysis Profile by Genova Diagnostics is a urinary assessment of 39 key organic acids, grouped according to their primary roles in four central areas of metabolism.

For gastrointestinal function, this profile measures eight markers that can reveal malabsorption and dysbiosis (a state of imbalanced gut microbial flora). These imbalances can be addressed to improve gut health, and to help prevent or alleviate common causes of nutritional deficiency, chronic digestive problems, yeast overgrowth (Candida), cognitive impairment, gastrointestinal distress, and degenerative conditions.

To evaluate the body’s production of energy, this profile assesses metabolites that serve as important intermediates in the citric acid cycle. This cycle supplies the body with its primary energy needs, converting 90% of food energy into cellular energy. This subpanel also includes carbohydrate metabolites that can signal impaired glucose (blood sugar) metabolism. Additional markers help evaluate the body’s breakdown of fats and its production of cholesterol and coenzyme Q10. Imbalances of cellular energy metabolites are linked with chronic fatigue, accelerated cell breakdown, and unhealthy aging.

A special grouping of neurotransmitter metabolites serve as important diagnostic indicators of abnormal metabolism that can underlie many key aspects of neuropsychiatric function. These markers are urinary metabolites of powerful neurotransmitters that act on the central nervous system-including epinephrine, dopamine, and serotonin-substances which can profoundly influence patterns of stress response, emotional well-being, cognition, and sleep.

Finally, this test provides a functional assessment of nutrient sufficiency and usage that covers a broad range of vitamins, coenzymes, elements, enzyme activators, and other nutrients. An analysis of amino acid metabolites which require vitamin and mineral cofactors for their metabolism can point to deficiencies of vitamins B6, B12, and C, magnesium, copper, iron, as well as various amino acids.

All markers on the Metabolic Analysis Profile are measured in urine and ratioed to creatinine. This allows a single urine sample to be used for analysis. The test report includes an in-depth interpretation for abnormal results with a list of possible remedial nutrients. Available with pediatric (ages 2-12) as well as adult reference ranges, this test is an important clinical tool for treating imbalances underlying metabolic, nutritional, and neurological disorders. Using test results, practitioners can design comprehensive, customized therapies to restore optimal metabolic health.

Assessment Specifics
Analytes:
Creatinine and 39 organic acids ratioed to creatinine, including:
8 gastrointestinal metabolites
13 cellular energy metabolites
4 neurotransmitter metabolites
14 amino acid metabolites

Specimen Requirements:
First morning urine collection; 2 tubes (samples frozen)

Before Taking this Test:
- Avoid taking creatine supplements (2 days before test)
- Check with healthcare provider about what other medications and supplements to avoid (4 days before test)
- Women should not collect urine during menses
- Arrange shipping for Monday-Thursday
- See instructions inside test kit for details

All lab tests can be done through the mail in the privacy of your own home, except blood tests, we send you to a lab to have your blood drawn for these. After you pay for the test we mail you the kit, the results take two weeks, the test results will be mailed to us and we will call you to go over the results, its that easy! All tests include the consultation for the report of findings.

Click on test of interest on the right for more information.

Call our office for details. 
800-956-7083 OR 818-707-3126