Evaluates
fourteen organic acids that play a pivotal role in the generation
of cell energy. Using a urine sample, the test can reveal metabolic
distress associated with generalized pain and fatigue, which may arise
in response to toxic exposure, nutrient imbalances, digestive dysfunction,
and other causes. The profile also analyzes mitochondrial dysfunction
and acquired errors of organic acid metals.
Plants synthesize and store energy from sunlight and nutrients. How
efficiently the human body recovers this energy from plants or animals
that eat plants can have a profound effect on physiological function.
Fundamentally, optimal health and well-being depends on the healthy
functioning of the cell. The mitochondria of each cell functions as
its energy "factory." The primary function of the mitochondria
is to efficiently produce the energy we require to live vital lives.
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The
Cellular Energy Profile measures a special grouping of organic acids.
These metabolites primarily reflect carbohydrate metabolism, mitochondrial
function, and oxidation of fatty acids that occurs during cellular
respiration. The organic acids measured in this panel are central
components or intermediates in metabolic pathways of energy conversion
related to the Kreb (citric acid) cycle and the production of ATP-the
cell's main fuel source.
Defects of mitochondrial
metabolism are associated with a wide spectrum of illness and disease.
This test can reveal metabolic distress that can arise from toxic
exposure, nutrient deficiency, intestinal dysbiosis, dysglycemia,
oxidative stress, poor diet, and other causes. The profile is particularly
relevant for the chronically "unwell" patient, who may
be experiencing multiple chemical sensitivities, fibromyalgia, fatigue,
malaise, hypotonia (loss of muscle tone), acid-base imbalance, low
exercise tolerance, muscle/joint pain, or headache.
Organic acids
also play a pivotal role in generating energy for muscle tissue.
For this reason, mitochondrial defects are associated with a variety
of neuromuscular disorders. Imbalances may also influence cardiac
function, glycemic control, and behavior. Moreover, because the
mitochondria modulate cell death, their dysfunction is closely linked
with the aging process and neurodegenerative diseases like Alzheimer's,
Parkinson's and ALS.
This test serves
as a diagnostic aid for acquired, as opposed to in-born, errors
of organic acid metabolism. Each analyte is reported in relation
to creatinine levels to ensure normal renal function and representative
results. Significantly abnormal findings may be due to inborn errors
if they persist after removal of toxics, nutrient supplementation,
dietary adjustments, and correction of intestinal dysbiosis or infection.
For these cases, further specialized follow-up testing is needed
to identify congenital organic acidopathies.
What
You Should Know:
This
test reveals important clinical information about:
- Thirteen organic
acids that specifically reflect carbohydrate metabolism, mitochondrial
function, and beta-oxidation of fatty acids
- Mitochondrial
dysfunction which may be underlying chronic symptoms of fibromyalgia,
fatigue, malaise, hypotonia (loss of muscle tone), acid-base imbalance,
low exercise tolerance, muscle/joint pain, or headache
- Acquired errors
of organic acid metabolism that can arise from toxic exposure, nutrient
deficiency, intestinal dysbiosis, dysglycemia, oxidative stress,
poor diet, and other causes.
Assessment Specifics
Analytes:
lactic acid
pyruvic acid
cis-aconitic acid
citric acid
isocitric acid
a-ketoglutaric acid
succinic acid
fumaric acid
malic acid
adipic acid
suberic acid
ß-hydroxy-ß-methyl-glutaric acid
ß-hydroxybutyric acid
Specimen
Requirement:
First early morning urine collection
All
lab tests can be done through the mail in the privacy of your own
home, except blood tests, we send you to a lab to have your blood
drawn for these. After you pay for the test we mail you the kit,
the results take two weeks, the test results will be mailed to us
and we will call you to go over the results, its that easy! All
tests include the consultation for the report of findings.
Click on test of interest on the right for more information
Call our office for details.
800-956-7083 OR 818-707-3126
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